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Synthetic Genome Drives Bacterial Cell

May 20th, 2010 05:04 admin Leave a comment Go to comments

Dr. Eggman writes “Physorg.com brings us news of a synthetic genome, produced by the J. Craig Venter Institute, being used in an existing bacterial cell for the first time. Using a combination of biological hosts, the technique produces short strings of DNA by machine which inserting them into yeast to be stitched together via DNA-repair enzymes. The medium sequences are passed into E. Coli and back into yeast. After three rounds, a genome of three million base pairs was produced.” (More below.)

“Specifically, the genome of M. mycoides was synthesized from scratch. This synthetic genome was then inserted into the cells of a bacteria known as Mycoplasm capricolum. The result is a cell, driven by a synthetic genome, producing not the proteins of Mycoplasm capricolum, but of M. mycoides. The institute has far-reaching plans for its synthetic life program, including designing algae that can capture carbon dioxide, make new hydrocarbons for refineries as well as making new chemicals or food ingredients, and speed up vaccine production.”

The BBC has coverage of the hybrid cell as well.

Source: Synthetic Genome Drives Bacterial Cell

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